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AI Learns to 'Speak' Genetic 'Dialect' for Future SARS-CoV-2 Mutation Prediction

A powerful AI model called Deep Novel Mutation Search (DNMS) predicts virus mutations more accurately and efficiently than traditional, time-consuming lab experiments. Focused on the SARS-CoV-2 spike protein, the model uses a specialized protein language model fine-tuned to understand the virus's specific "language." DNMS can predict mutations that cause small, functional changes - crucial for viruses like SARS-CoV-2, which evolve through subtle adjustments to maintain function.

March 27, 2025


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