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CD47 Protein Crucial for Bone Fracture Healing, Study Reveals

A new discovery has shed new light on the crucial role of the CD47 protein in bone fracture healing. Scientists have identified CD47 as an essential regulator of mesenchymal progenitor cell (MSC) proliferation--cells critical for bone repair. Without CD47, bone healing was significantly delayed, with reduced callus formation and diminished bone volume in both normal and ischemic fracture models. These findings suggest that targeting CD47 could pave the way for novel therapeutic strategies to enhance fracture recovery, particularly in cases where blood supply is compromised.

March 26, 2025


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