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A New Approach to Asthma Treatment: Harnessing the Liver to Reprogram the Immune System

Researchers developed liver-targeted immunotherapy (LIT), a novel approach that chemically modifies allergens with mannose sugars, directing them to the liver where immune tolerance develops. In preclinical trials, just two LIT doses provided year-long asthma protection without triggering allergic reactions, outperforming traditional immunotherapy.

April 16, 2025


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